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American Society of Anesthesiologists Annual Meeting

Researchers from around the world are presenting nearly 100 scientific posters and sessions referencing BIS technology at the American Society of Anesthesiologists (ASA) Annual Meeting in Chicago this week. BIS monitoring, developed by Aspect Medical Systems, Inc., is the world's level-of-consciousness monitoring technology for measuring the effects of anesthetics and sedatives on the brain. BIS-related research presented at the meeting of more than 5, 000 anesthesiologists covers a broad spectrum of topics including short and long term outcome benefits of BIS monitoring, intraoperative awareness and the role of fluctuations in BIS values in assessing pain both during and after surgery.

Research being presented at ASA that is supported by Aspect include two studies that evaluated how rapid changes in BIS values and EMG may be useful in assessing patient response to pain during surgery. The first study demonstrated that BIS values and EMG show greater and more frequent fluctuations before a patient responded (e.g. moved) in reaction to painful surgical events. The second study demonstrated that highly variable BIS and EMG measurements during surgery were associated with patients reporting greater pain during recovery.

A third study explored the relationship between depth of consciousness (as measured by BIS) and changes in inflammatory biomarkers after surgery. This prospective, randomized study compared BIS-guided anesthetic with standard clinical practice to determine the effects of minimizing exposure to anesthetics on inflammatory response. Patients in the BIS monitored group received 33 percent less anesthetic and showed a less severe inflammatory response compared to controls.



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